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CASE 6

 
This 78 years old woman was treated with radiotherapy in 1994 for bilateral breast cancer.  Now she has developed 3 dermal tumor nodes measuring 10mm, 20mm and 50mm in diameter bulging the overlaying skin laterally, medial-caudally  and medial-cranially around the nipple.  She had right breast amputation.  The tissue presented here slide was made from the 20mm medio-caudal node.  Macroscopically tissue appears rich on blood vessels. Immunohistological work up showed expression of CD34 and Vimentin on solid and capillary parts of the tissue. The CD31 receptor is detected especially on capillaries and cavernous parts.  There is also positive factor VIII.  In the solid parts there is low expression of Cytokeratine and smooth muscle Actin. Case presented by:

Valeria Renz,MD
Institute for Pathology Charite
Berlin, Germany

Send your answers to: Valeria Renz

 

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